Yazar "Ceyhan, Deniz" için listeleme
-
7,8-Dihydroxycoumarin derivatives: In silico molecular docking and in vitro anticholinesterase activity
Özdemir, Mücahit; Taşkın, Duygu; Ceyhan, Deniz; Koksoy, Baybars; Taşkın, Turgut; Bulut, Mustafa; Yalçın, Bahattin (Elsevier, 2023)In this study, acetylcholinesterase enzyme (AChE) inhibition potential and antioxidant activity of eight different coumarin derivatives together with two ( 5 and 8 ) newly synthesized coumarins were investigated. The results ... -
Design and in silico study of the novel coumarin derivatives against SARS-CoV-2 main enzymes
Özdemir, Mücahit; Köksoy, Baybars; Ceyhan, Deniz; Sayın, Koray; Erçağ, Erol; Bulut, Mustafa; Yalçın, Bahattin (Taylor and Francis Ltd., 2020)The novel coronavirus (SARS-CoV-2) causes severe acute respiratory syndrome and can be fatal. In particular, antiviral drugs that are currently available to treat infection in the respiratory tract have been experienced, ... -
Effects of calcium hydroxide and N-acetylcysteine on MMP-2, MMP-9, TIMP-1 and TIMP-2 in LPS-stimulated macrophage cell lines
Astantas, Eda Ezgi; Aksoy, Yasemin; Ulum, Yeliz Zulfiye Akkaya; Ceyhan, Deniz; Peynircioglu, Banu; Buzoğlu, Hatice Doğan (Walter De Gruyter Gmbh, 2018)Aim: This study was evaluated the effects of N-acetylcysteine (NAC) and calcium hydroxide (Ca(OH)(2)) on the expression levels of matrix metalloproteinase -2, -9 (MMP-2, -9) and tissue inhibitor metalloproteinase -1, -2 ... -
In silico, 6lu7 protein inhibition using dihydroxy-3-phenyl coumarin derivatives for SARS-CoV-2
Özdemir, Mücahit; Köksoy, Baybars; Ceyhan, Deniz; Bulut, Mustafa; Yalçın, Bahattin (Turkish Chemical Society, 2020)The new emerging coronavirus (SARS-CoV-2) has become a global health problem with very rapid transmission from person to person, causing severe acute respiratory problems. In the circumstance, the discovery of vaccines or ... -
Novel binuclear antimony(III) halide complexes of 5-methoxy-2-mercaptobenzimidazole: synthesis, structural characterization, and biological studies
Öztürk, İbrahim İsmet; Yarar, Sinem; Gürgan, Muazzez; Ceyhan, Deniz; Panagiotou, Nikos; Tasiopoulos, Anastasios J.; Aral, Cenk (Taylor and Francis Ltd., 2020)The new binuclear antimony(III) complexes corresponding to the formulas [SbCl3(µ2-S)(MtMBZIM)2]2 (1), {[SbBr2(µ2-Br)(MtMBZIM)2]2·H2O} (2) and {[SbI2(µ2-I)(MtMBZIM)2]2·H2O} (3) (MtMBZIM: 5-methoxy-2-mercaptobenzimidazole) ... -
Structural and biological features of bismuth(III) halide complexes with heterocyclic thioamides
Öztürk, İbrahim İsmet; Şirinkaya, Emine T.; Çakmak, Mehmet; Gürgan, Muazzez; Ceyhan, Deniz; Panagiotou, Nikos; Tasiopoulos, Anastasios J. (Elsevier B.V., 2021)Ten novel bismuth(III) halide complexes of [Bi(L)X3]n, [Bi(L)2×3]2, and [Bi(L)3×3] structural types were synthesized, in which L: 5-ethoxy-2-mercaptobenzimidazole, 5?methoxy-2-mercaptobenzimidazole and N-methylbenzothiazole. ... -
Synthesis and molecular docking study of novel COVID-19 inhibitors
Gerçek, Zuhal; Ceyhan, Deniz; Erçağ, Erol (Scientific Technical Research Council Turkey-Tubitak, 2021)In 2020, the world tried to combat the corona virus (COVID-19) pandemic. A proven treatment method specific to Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is still not found. In this study, seven new ... -
Synthesis and molecular docking study of novel COVID-19 inhibitors
GERÇEK, Z.; Ceyhan, Deniz; Erçağ, Erol (TUBITAK, 2021)In 2020, the world tried to combat the corona virus (COVID-19) pandemic. A proven treatment method specific to Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is still not found. In this study, seven new ... -
Synthesis, characterization and biological evaluation of novel antimony(III) iodide complexes with tetramethylthiourea and N-ethylthiourea
Öztürk, İbrahim İsmet; Yarar, S.; Gürgan, Muazzez; Ceyhan, Deniz; Banti, Christina N.; Hadjikakou, Sotiris K.; Tasiopoulos, Anastasios J. (Elsevier S.A., 2019)Novel trivalent antimony(III) complexes with tetramethylthiourea (TMTU) and N-ethylthiourea (NETU) were synthesized by the reaction of antimony(III) iodide (SbI3). Antimony(III) iodide complexes of formulae {[SbI2(µ2-I)(TMTU)2]2} ...